Evaluating Suspected Cardiac Amyloidosis

Manish Motwani; Parthiban Arumugam; Alberto Rocci; Luigi Venetucci

doi:10.1016/j.jaccas.2019.06.027

Evaluating Suspected Cardiac Amyloidosis

JACC Case Rep. 2019 Aug 21;1(2):141-145. doi: 10.1016/j.jaccas.2019.06.027. eCollection 2019 Aug.

Authors

Manish Motwani^{1

2}, Parthiban Arumugam³, Alberto Rocci^{4

5}, Luigi Venetucci^{1

2}

Affiliations

¹ Manchester Heart Centre, Manchester Royal Infirmary, Manchester University NHS Foundation Trust, Manchester, United Kingdom.
² Institute of Cardiovascular Sciences, University of Manchester, Manchester, United Kingdom.
³ Nuclear Medicine Centre, Manchester Royal Infirmary, Manchester University NHS Foundation Trust, Manchester, United Kingdom.
⁴ Division of Cancer Sciences, University of Manchester, Manchester, United Kingdom.
⁵ Department of Clinical Haematology, Manchester Royal Infirmary, Manchester University NHS Foundation Trust, Manchester, United Kingdom.

Abstract

A 71-year-old-woman presented with breathlessness, general tiredness and orthopnea. Echocardiography and electrocardiogram were suspicious for cardiac amyloidosis. This case illustrates contemporary evaluation to confirm the diagnosis and distinguish between different types of amyloid. (Level of Difficulty: Beginner.).

Keywords: AL, light-chain amyloidosis; ATTR, amyloid transthyretin; CA, cardiac amyloidosis; DPD, 2,3-dicarboxypropane-1,1-diphosphonate; ECG, electrocardiogram; FLC, free light chain; LV, left ventricular; LVH, left ventricular hypertrophy; SPECT, single-photon emission computed tomography; TTE, transthoracic echocardiography; cardiac magnetic resonance; echocardiography; electrocardiogram; imaging; nuclear medicine; restrictive.

Publication types

Case Reports