Treatable cerebellar ataxias

Divya K P; Asha Kishore

doi:10.1016/j.prdoa.2020.100053

Treatable cerebellar ataxias

Clin Park Relat Disord. 2020 Apr 4:3:100053. doi: 10.1016/j.prdoa.2020.100053. eCollection 2020.

Authors

Divya K P¹, Asha Kishore¹

Affiliation

¹ Department of Neurology, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Trivandrum, Kerala 695011, India.

Abstract

Cerebellar ataxic syndrome is a heterogenous class of disorders which can result from a miscellany of causes- genetic or acquired. There are a few metabolic, immune mediated, inflammatory and hereditary causes of ataxia which can be diagnosed from the gamut of possibilities, offering great relief to the ailing patient, their family and the treating physician. A pragmatic algorithm for diagnosing treatable causes of ataxia includes a thorough clinical history, meticulous examination for associated signs and an investigative mind to clinch the diagnosis. With novel diagnostic techniques and targeted therapies, early diagnosis and treatment can lead to favourable outcomes. In this review, diseases presenting predominantly as cerebellar ataxia and are treatable by targeted therapies are discussed.

Keywords: Acute ataxia; Cerebellar ataxia; Genetic ataxia; Treatable ataxia.

Publication types

Review