Acral multiple symmetrical palisaded encapsulated neuromas: A rare case report and review of the literature

Abstract

Palisaded encapsulated neuroma (PEN) is a benign neoplasm composed of nerve tissue. It typically presents as isolated, asymptomatic, skin-colored papules or nodules on the face, neck, or oral mucosa of the middle-aged and elderly. Here, we reported a very unusual and unique case of acral multiple symmetrical PENs with no obvious systemic abnormalities and reviewed the published work on acral PEN.

Keywords: case report; neuroma; palisaded encapsulated neuroma; solitary circumscribed neuroma.