Soft tissue and visceral sarcomas: ESMO-EURACAN-GENTURIS Clinical Practice Guidelines for diagnosis, treatment and follow-up☆

A Gronchi; A B Miah; A P Dei Tos; N Abecassis; J Bajpai; S Bauer; R Biagini; S Bielack; J Y Blay; S Bolle; S Bonvalot; I Boukovinas; J V M G Bovee; K Boye; B Brennan; T Brodowicz; A Buonadonna; E De Álava; X G Del Muro; A Dufresne; M Eriksson; F Fagioli; A Fedenko; V Ferraresi; A Ferrari; A M Frezza; S Gasperoni; H Gelderblom; F Gouin; G Grignani; R Haas; A B Hassan; S Hecker-Nolting; N Hindi; P Hohenberger; H Joensuu; R L Jones; C Jungels; P Jutte; L Kager; B Kasper; A Kawai; K Kopeckova; D A Krákorová; A Le Cesne; F Le Grange; E Legius; A Leithner; A Lopez-Pousa; J Martin-Broto; O Merimsky; C Messiou; O Mir; M Montemurro; B Morland; C Morosi; E Palmerini; M A Pantaleo; R Piana; S Piperno-Neumann; P Reichardt; P Rutkowski; A A Safwat; C Sangalli; M Sbaraglia; S Scheipl; P Schöffski; S Sleijfer; D Strauss; S Strauss; K Sundby Hall; A Trama; M Unk; M A J van de Sande; W T A van der Graaf; W J van Houdt; T Frebourg; P G Casali; S Stacchiotti; ESMO Guidelines Committee, EURACAN and GENTURIS. Electronic address: clinicalguidelines@esmo.org

doi:10.1016/j.annonc.2021.07.006

Soft tissue and visceral sarcomas: ESMO-EURACAN-GENTURIS Clinical Practice Guidelines for diagnosis, treatment and follow-up^☆

Ann Oncol. 2021 Nov;32(11):1348-1365. doi: 10.1016/j.annonc.2021.07.006. Epub 2021 Jul 22.

Authors

A Gronchi¹, A B Miah², A P Dei Tos³, N Abecassis⁴, J Bajpai⁵, S Bauer⁶, R Biagini⁷, S Bielack⁸, J Y Blay⁹, S Bolle¹⁰, S Bonvalot¹¹, I Boukovinas¹², J V M G Bovee¹³, K Boye¹⁴, B Brennan¹⁵, T Brodowicz¹⁶, A Buonadonna¹⁷, E De Álava¹⁸, X G Del Muro¹⁹, A Dufresne²⁰, M Eriksson²¹, F Fagioli²², A Fedenko²³, V Ferraresi²⁴, A Ferrari²⁵, A M Frezza²⁶, S Gasperoni²⁷, H Gelderblom²⁸, F Gouin²⁹, G Grignani³⁰, R Haas³¹, A B Hassan³², S Hecker-Nolting⁸, N Hindi³³, P Hohenberger³⁴, H Joensuu³⁵, R L Jones³⁶, C Jungels³⁷, P Jutte³⁸, L Kager³⁹, B Kasper³⁴, A Kawai⁴⁰, K Kopeckova⁴¹, D A Krákorová⁴², A Le Cesne⁴³, F Le Grange⁴⁴, E Legius⁴⁵, A Leithner⁴⁶, A Lopez-Pousa⁴⁷, J Martin-Broto³³, O Merimsky⁴⁸, C Messiou⁴⁹, O Mir⁵⁰, M Montemurro⁵¹, B Morland⁵², C Morosi⁵³, E Palmerini⁵⁴, M A Pantaleo⁵⁵, R Piana⁵⁶, S Piperno-Neumann⁵⁷, P Reichardt⁵⁸, P Rutkowski⁵⁹, A A Safwat⁶⁰, C Sangalli⁶¹, M Sbaraglia³, S Scheipl⁴⁶, P Schöffski⁶², S Sleijfer⁶³, D Strauss⁶⁴, S Strauss⁴⁴, K Sundby Hall¹⁴, A Trama⁶⁵, M Unk⁶⁶, M A J van de Sande⁶⁷, W T A van der Graaf⁶⁸, W J van Houdt⁶⁹, T Frebourg⁷⁰, P G Casali⁷¹, S Stacchiotti²⁵; ESMO Guidelines Committee, EURACAN and GENTURIS. Electronic address: clinicalguidelines@esmo.org

Affiliations

¹ Department of Surgery, Fondazione IRCCS Istituto Nazionale dei Tumori and University of Milan, Milan, Italy.
² Department of Oncology, Royal Marsden Hospital and Institute of Cancer Research, London, UK.
³ Department of Pathology, Azienda Ospedale Università Padova, Padua, Italy.
⁴ Instituto Portugues de Oncologia de Lisboa Francisco Gentil, EPE, Lisbon, Portugal.
⁵ Department of Medical Oncology, Tata Memorial Centre, Homi Bhabha National Institute, Mumbai, India.
⁶ Department of Medical Oncology, Interdisciplinary Sarcoma Center, West German Cancer Center, University of Duisburg-Essen, Essen, Germany.
⁷ Department of Oncological Orthopedics, IRCCS Regina Elena National Cancer Institute, Rome, Italy.
⁸ Klinikum Stuttgart-Olgahospital, Stuttgart, Germany.
⁹ Centre Leon Berard and UCBL1, Lyon, France.
¹⁰ Radiation Oncology Department, Gustave Roussy, Villejuif, France.
¹¹ Department of Surgery, Institut Curie, Paris, France.
¹² Bioclinic Thessaloniki, Thessaloniki, Greece.
¹³ Department of Pathology, Leiden University Medical Center, Leiden, The Netherlands.
¹⁴ Department of Oncology, Oslo University Hospital, The Norwegian Radium Hospital, Oslo, Norway.
¹⁵ Paediatric Oncology, Royal Manchester Children's Hospital, Manchester, UK.
¹⁶ Vienna General Hospital (AKH), Medizinische Universität Wien, Vienna, Austria.
¹⁷ Centro di Riferimento Oncologico di Aviano, Aviano, Italy.
¹⁸ Hospital Universitario Virgen del Rocio-CIBERONC, Seville, Spain; Department of Normal and Pathological Cytology and Histology, School of Medicine, University of Seville, Seville, Spain.
¹⁹ Integrated Unit ICO Hospitalet, HUB, Barcelona, Spain.
²⁰ Département d'Oncologie Médicale, Centre Leon Berard, Lyon, France.
²¹ Skane University Hospital-Lund, Lund, Sweden.
²² Paediatric Onco-Haematology Department, Regina Margherita Children's Hospital, Department of Public Health and Pediatrics, University of Turin, Turin, Italy.
²³ P. A. Herzen Cancer Research Institute, Moscow, Russian Federation.
²⁴ Sarcomas and Rare Tumors Unit, IRCCS Regina Elena National Cancer Institute, Rome, Italy.
²⁵ Pediatric Oncology Unit, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.
²⁶ Department of Cancer Medicine, Fondazione IRCCS Istituto Nazionale Tumori, Milan, Italy.
²⁷ Azienda Ospedaliera Universitaria Careggi Firenze, Florence, Italy.
²⁸ Department of Medical Oncology, Leiden University Medical Centre, Leiden, The Netherlands.
²⁹ Centre Leon-Berard Lyon, Lyon, France.
³⁰ Candiolo Cancer Institute, FPO - IRCCS, Candiolo, Italy.
³¹ Department of Radiotherapy, The Netherlands Cancer Institute, Amsterdam, The Netherlands; Department of Radiotherapy, Leiden University Medical Centre, Leiden, The Netherlands.
³² Oxford University Hospitals NHS Foundation Trust and University of Oxford, Oxford, UK.
³³ Department of Medical Oncology, Fundación Jimenez Diaz University Hospital, Advanced Therapies in Sarcoma Lab, Madrid, Spain.
³⁴ Mannheim University Medical Center, Mannheim, Germany.
³⁵ Helsinki University Hospital (HUH) and University of Helsinki, Helsinki, Finland.
³⁶ Sarcoma Unit, Royal Marsden Hospital and Institute of Cancer Research, London, UK.
³⁷ Medical Oncology Clinic, Institut Jules Bordet, Université Libre de Bruxelles, Brussels, Belgium.
³⁸ University Medical Center Groningen, Groningen, The Netherlands.
³⁹ St. Anna Children's Hospital, Department of Pediatrics and Medical University Vienna Children's Cancer Research Institute, Vienna, Austria.
⁴⁰ Department of Musculoskeletal Oncology, National Cancer Center Hospital, Tokyo, Japan.
⁴¹ University Hospital Motol, Prague, Czech Republic.
⁴² Masaryk Memorial Cancer Institute, Brno, Czech Republic.
⁴³ Department of Cancer Medicine, Gustave Roussy, Villejuif, France.
⁴⁴ Department of Oncology, University College London Hospitals NHS Foundation Trust (UCLH), London, UK.
⁴⁵ Department for Human Genetics, University Hospitals Leuven, KU Leuven, Leuven, Belgium.
⁴⁶ Department of Orthopaedics and Trauma, Medical University of Graz, Graz, Austria.
⁴⁷ Medical Oncology Department, Hospital Universitario Santa Creu i Sant Pau, Barcelona, Spain.
⁴⁸ Tel Aviv Sourasky Medical Center (Ichilov), Tel Aviv, Israel.
⁴⁹ Department of Radiology, Royal Marsden Hospital and Institute of Cancer Research, London, UK.
⁵⁰ Department of Ambulatory Cancer Care, Gustave Roussy, Villejuif, France.
⁵¹ Department of Oncology, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland.
⁵² Birmingham Women's and Children's NHS Foundation Trust, Birmingham, UK.
⁵³ Department of Radiology, IRCCS Foundation National Cancer Institute, Milan, Italy.
⁵⁴ Department of Osteoncology, Bone and Soft Tissue Sarcomas and Innovative Therapies, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy.
⁵⁵ Division of Oncology, IRCCS Azienda Ospedaliero-Universitaria, di Bologna, Bologna, Italy.
⁵⁶ Azienda Ospedaliero, Universitaria Città della Salute e della Scienza di Torino, Turin, Italy.
⁵⁷ Department of Medical Oncology, Institut Curie, Paris, France.
⁵⁸ Helios Klinikum Berlin Buch, Berlin, Germany.
⁵⁹ Department of Soft Tissue/Bone Sarcoma and Melanoma, Maria Skłodowska-Curie National Research Institute of Oncology, Warsaw, Poland.
⁶⁰ Aarhus University Hospital, Aarhus, Denmark.
⁶¹ Department of Radiotherapy, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.
⁶² Department of General Medical Oncology, University Hospitals Leuven, Leuven Cancer Institute, Leuven, Belgium.
⁶³ Department of Medical Oncology, Erasmus MC Cancer Institute, Rotterdam, The Netherlands.
⁶⁴ Department of Surgery, Royal Marsden Hospital, London, UK.
⁶⁵ Department of Research, Evaluative Epidemiology Unit, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.
⁶⁶ Institute of Oncology of Ljubljana, Ljubljana, Slovenia.
⁶⁷ Department of Orthopedic Surgery, Leiden University Medical Center, Leiden, The Netherlands.
⁶⁸ Department of Medical Oncology, Erasmus MC Cancer Institute, Rotterdam, The Netherlands; Department of Medical Oncology, the Netherlands Cancer Institute, Amsterdam, The Netherlands.
⁶⁹ Department of Surgical Oncology, the Netherlands Cancer Institute, Amsterdam, The Netherlands.
⁷⁰ Department of Genetics, Normandy Center for Genomic and Personalized Medicine, Normandie Univ, UNIROUEN, Inserm U1245 and Rouen University Hospital, Rouen, France.
⁷¹ Department of Cancer Medicine, Fondazione IRCCS Istituto Nazionale Tumori, Milan, Italy; Department of Oncology and Hemato-oncology University of Milan, Milan, Italy.

PMID: 34303806
DOI: 10.1016/j.annonc.2021.07.006

No abstract available

Keywords: Clinical Practice Guideline; desmoid; retroperitoneal sarcoma; sarcoma; soft tissue sarcomas; uterine sarcoma.

Publication types

Practice Guideline
Research Support, Non-U.S. Gov't

MeSH terms

Follow-Up Studies
Humans
Sarcoma* / diagnosis
Sarcoma* / epidemiology
Sarcoma* / therapy
Soft Tissue Neoplasms* / diagnosis
Soft Tissue Neoplasms* / epidemiology
Soft Tissue Neoplasms* / therapy