In vitro inhibitory activities of sugarcane extract on avian Eimeria sporozoites

Int J Parasitol Drugs Drug Resist. 2021 Dec:17:1-4. doi: 10.1016/j.ijpddr.2021.07.001. Epub 2021 Jul 8.

Abstract

The current in vitro study aimed to investigate the effects of a processed sugarcane extract on the viability of avian Eimeria sporozoites. Treatments were applied to hatched sporozoites: 1) without additives (no-treatment control); 2) with ethanol; 3) with salinomycin; 4) with Polygain™. All treatments were incubated in RPMI media containing live sporozoites at 37 °C for 14 h and then the number of viable sporozoites were counted. Compared to the no-treatment control, Polygain™ decreased (P < 0.001) the counts of E. maxima, E. acervulina, E. bruneti, and E. mitis sporozoites to a level similar to salinomycin (P > 0.05). In conclusion, Polygain™ could be a potential candidate as an anticoccidial agent.

Keywords: Anticoccidial agents; Avian coccidiosis; Eimeria species; In vitro excystation; Sporozoites; Sugarcane extract.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Chickens
  • Coccidiosis* / drug therapy
  • Coccidiosis* / veterinary
  • Eimeria*
  • Plant Extracts / pharmacology
  • Poultry Diseases* / drug therapy
  • Saccharum*
  • Sporozoites

Substances

  • Plant Extracts