Ficolin A exacerbates severe H1N1 influenza virus infection-induced acute lung immunopathological injury via excessive complement activation

Affiliations

• ¹ Department of Immunology, School of Basic Medical Sciences, Capital Medical University, Beijing, China.
• ² Department of Respiratory Medicine, Hunan Provincial People's Hospital (The First Affiliated Hospital of Hunan Normal University), Changsha, China.
• ³ NHC Key Laboratory of Human Disease Comparative Medicine (The Institute of Laboratory Animal Sciences, CAMS & PUMC), Beijing Key Laboratory for Animal Models of Emerging and Reemerging Infection, Beijing, China.
• ⁴ China-Japan Friendship Hospital, National Clinical Research Center for Respiratory Diseases, Clinical Center for Pulmonary Infections, Capital Medical University, Beijing, China.
• ⁵ Department of Core Facility Center, Capital Medical University, Beijing, China.
• ⁶ China-Japan Friendship Hospital, National Clinical Research Center for Respiratory Diseases, Clinical Center for Pulmonary Infections, Capital Medical University, Beijing, China. caobin_ben@163.com.
• ⁷ Institute of Respiratory Medicine, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, China. caobin_ben@163.com.
• ⁸ Tsinghua University-Peking University Joint Center for Life Sciences, Beijing, China. caobin_ben@163.com.
• ⁹ Department of Immunology, School of Basic Medical Sciences, Capital Medical University, Beijing, China. zhxlwl@ccmu.edu.cn.