Comparison of the Visual Outcomes of an Extended Depth-of-Focus Lens and a Trifocal Lens

Majid Moshirfar; James Ellis; Daniel Beesley; Shannon E McCabe; Adam Lewis; William B West; Yasmyne Ronquillo; Phillip Hoopes

doi:10.2147/OPTH.S321779

Comparison of the Visual Outcomes of an Extended Depth-of-Focus Lens and a Trifocal Lens

Clin Ophthalmol. 2021 Jul 16:15:3051-3063. doi: 10.2147/OPTH.S321779. eCollection 2021.

Authors

Majid Moshirfar^{1

2

3}, James Ellis⁴, Daniel Beesley⁵, Shannon E McCabe^{1

6}, Adam Lewis⁷, William B West⁴, Yasmyne Ronquillo¹, Phillip Hoopes¹

Affiliations

¹ Hoopes Vision Research Center, Hoopes Vision, Draper, UT, USA.
² John A. Moran Eye Center, Department of Ophthalmology and Visual Sciences, University of Utah, Salt Lake City, UT, USA.
³ Utah Lions Eye Bank, Murray, UT, USA.
⁴ University of Utah School of Medicine, Salt Lake City, UT, USA.
⁵ Brigham Young University, Provo, UT, USA.
⁶ Mission Hills Eye Center, Pleasant Hill, CA, USA.
⁷ Kansas City University College of Osteopathic Medicine, Kansas City, MO, USA.

Abstract

Purpose: To compare the visual performance of the AcrySof IQ PanOptix trifocal intraocular lens and the TECNIS Symfony extended depth-of-focus lens at near and distance visual ranges.

Methods: A total of 146 patients (221 eyes) who underwent phacoemulsification and cataract extraction and received either a PanOptix or Symfony lens from January 2019 to July 2020 were included in the study (83 PanOptix non-toric, 30 PanOptix toric, 70 Symfony non-toric, and 38 Symfony toric). Uncorrected distance (UDVA), uncorrected near (UNVA), and corrected distance (CDVA) visual acuity were assessed at one-day, one-month, and three-months postoperatively. Averages of UDVA, UNVA, and CDVA were taken to evaluate which lens was superior at near and distance visual ranges. Secondary outcome measures including glare, halo, dryness, and problems with night vision were documented at each postoperative visit.

Results: At one month postoperatively, the average UNVA was 0.16 ± 0.14 logMAR in the PanOptix group and 0.21 ± 0.14 logMAR in the Symfony group (P=0.007); the average UDVA for the PanOptix group was 0.09 ± 0.13 logMAR compared to the Symfony group at 0.10 ± 0.14 logMAR (P=0.67); and the average CDVA was 0.02 ± 0.05 logMAR in the PanOptix group and 0.00 ± 0.04 logMAR in the Symfony group (P=0.11). At three months postoperatively, there were no statistically significant differences in UNVA, UDVA, or CDVA between the two groups (P=0.18, 0.79, 0.68 respectively). There was no statistically significant difference in secondary outcome measures at one- and three-months (P=0.49, 0.10 respectively).

Conclusion: The AcrySof IQ PanOptix trifocal intraocular lens appears to afford better UNVA compared to the TECNIS Symfony extended depth-of-focus intraocular lens at one-month postoperatively, though this difference was not seen at three months postoperatively. There is no statistically significant difference in UDVA and CDVA between the two groups at postoperative day one, one-month, and three-months.

Keywords: extended depth-of-focus lens; intraocular lens; trifocal lens; visual acuity.

Grants and funding

This study was funded by an unrestricted grant from Research to Prevent Blindness (RPB), 360 Lexington Avenue, 22nd Floor New York, NY 10017. No support was received for the publication of this article.