Transient hypertriglyceridaemia associated with propranolol for treatment of infantile hemangioma

Australas J Dermatol. 2021 Nov;62(4):e580-e581. doi: 10.1111/ajd.13669. Epub 2021 Jul 22.

Abstract

We present a case of a one-month-old female patient with severe hypertriglyceridaemia as a side effect of treating an ulcerating infantile hemangioma with systemic propranolol. The remarkedly rapid increase in triglyceride returned to normal 96 hours after the discontinuation of the medication, and further follow-up revealed normalisation of the lipid profile. Further research is necessary to unveil the association of systemic propranolol with hypertriglyceridaemia.

Keywords: beta blocker; hypertriglyceridaemia; infantile hemangioma; propranolol.

Publication types

  • Case Reports

MeSH terms

  • Adrenergic beta-Antagonists / adverse effects*
  • Female
  • Hemangioma / drug therapy*
  • Hemangioma / pathology
  • Humans
  • Hypertriglyceridemia / chemically induced*
  • Infant
  • Propranolol / adverse effects*
  • Skin Neoplasms / drug therapy*
  • Skin Neoplasms / pathology

Substances

  • Adrenergic beta-Antagonists
  • Propranolol