Prevalence of peri-implantitis in a sample of HIV-positive patients

Clin Exp Dent Res. 2021 Dec;7(6):1002-1013. doi: 10.1002/cre2.469. Epub 2021 Jul 20.

Abstract

Objectives: This study aimed to assess the prevalence of peri-implantitis in human immunodeficiency virus (HIV)-positive patients and the presence of a possible correlation between the immunological profile and serological values, of peri-implantitis, and of possible differences between all-on-4 and single crown/bridge prostheses.

Subjects and methods: This retrospective study included 58 adult HIV-positive patients (222 implants) with either all-in-4 prostheses or single crowns/bridges on at least one dental implant loaded for more than a year who were followed for 3 year (mean follow-up). Data pertaining to the probing pocket depth (PPD), bleeding on probing, and immunological and systemic profile were collected.

Results: Patients with single crown/bridge implant rehabilitation showed higher prevalence of peri-implantitis (34%) than patients with all-on-4 rehabilitation (0%) (p = 0.012). Patients with all-on-4 rehabilitation were significantly older than those with single crowns/bridges (p = 0.004). Patients with peri-implantitis had implants for a significantly longer duration than those without (p = 0.001), implying that the probability of peri-implantitis increases as the age of implant increases.

Conclusions: The prevalence of peri-implantitis was 26% in the HIV-positive patients population. No correlation was found between patients' immunological and serological factors and peri-implantitis. The most important risk factor for peri-implantitis and mucositis was implant age.

Trial registration: ClinicalTrials.gov NCT04829968.

Keywords: HIV-positive patients; all-on-4; mucositis; peri-implantitis.

MeSH terms

  • Adult
  • Dental Implants*
  • HIV Infections* / complications
  • HIV Infections* / epidemiology
  • Humans
  • Peri-Implantitis* / epidemiology
  • Peri-Implantitis* / etiology
  • Prevalence
  • Retrospective Studies

Substances

  • Dental Implants

Associated data

  • ClinicalTrials.gov/NCT04829968