Abstract
Herein, we report, for the first time, a Pd6L8(NO3)5.4(ICG)6.6 (ICG = indocyanine green) cage-based hexagonal nanoplate (3) via a combined nanoprecipitation and solid-state anion-exchange approach. Nanoplate 3 possesses enhanced near-infrared (NIR) light-triggered 1O2 generation, high cellular uptake selective lysosome-targeting ability, and, consequently, excellent antineoplastic activity.
MeSH terms
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Antineoplastic Agents / chemistry
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Antineoplastic Agents / pharmacology*
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Cell Proliferation / drug effects
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Drug Screening Assays, Antitumor
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Humans
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Infrared Rays
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MCF-7 Cells
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Metal-Organic Frameworks / chemistry
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Metal-Organic Frameworks / pharmacology*
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Molecular Structure
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Nanoparticles / chemistry*
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Particle Size
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Photochemotherapy
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Photosensitizing Agents / chemistry
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Photosensitizing Agents / pharmacology*
Substances
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Antineoplastic Agents
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Metal-Organic Frameworks
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Photosensitizing Agents