Larynx lymphoepithelial carcinoma: surgical management

BMJ Case Rep. 2021 Jul 20;14(7):e241460. doi: 10.1136/bcr-2020-241460.

Abstract

Lymphoepithelial carcinoma (LEC) is an entity mostly frequent in the nasopharynx, which represents 40% of all neoplasms. The incidence's not exclusive of a geographic area; however, it has an endemic distribution in Southeast Asia and Eskimos. LEC is not exclusive of the nasopharynx, has also been reported in other anatomical areas, such as the sinonasal tract, nasolacrimal duct, oral cavity, oropharynx, salivary glands, thymus, hypopharynx, oesophagus, stomach, trachea, lung and others. Non-nasopharyngeal and nasopharyngeal LEC have the same microscopic features, but the nasopharyngeal is more likely associated with Epstein-Barr virus. LEC has been approved by the WHO. LEC located in the larynx is quite rare and worthy of attention for its implication in the treatment and prognosis. We present a case of LEC treated in our ENT department in a middle-aged man.

Keywords: ear; head and neck cancer; nose and throat/otolaryngology; otolaryngology / ENT.

Publication types

  • Case Reports

MeSH terms

  • Carcinoma, Squamous Cell*
  • Epstein-Barr Virus Infections*
  • Herpesvirus 4, Human
  • Humans
  • Laryngeal Neoplasms*
  • Larynx*
  • Male
  • Middle Aged