BATF targets T cell exhaustion for termination

Nat Immunol. 2021 Aug;22(8):936-938. doi: 10.1038/s41590-021-00978-2.

Abstract

New reports glean further insight into the role of the transcription factor BATF in pivoting the differentiation of CD8+ T cells away from undergoing T cell exhaustion and facilitating transition of these cells into potent effectors.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Comment

MeSH terms

  • Basic-Leucine Zipper Transcription Factors* / genetics
  • T-Lymphocytes*

Substances

  • Basic-Leucine Zipper Transcription Factors