Clinical evaluation of efficacy and tolerance of a skin reconditioning compound for anti-aging

J Biol Regul Homeost Agents. 2021 Mar-Apr;35(2 Suppl. 1):217-226. doi: 10.23812/21-2supp1-23.

Abstract

Facial aging involves all facial structures located at different levels: bones soft tissues and skin with a reduction of the extracellular matrix. The aim of the study was to evaluate the efficacy of the injectable solution antiaging complex composed by non-reticulated hyaluronic acid (HA) and amino acids vitamins and antioxidants conveyed with mesotherapy technique in subjects with different expressions of aging. 114 patients with different expressions of aging were enrolled in this study with mean age (49±6). HA and amino acids vitamins and antioxidants complex solution Neofound (Love Cosmedical, Castagneto, Italy) was injected on the dermal plane or superficial subdermal plane. Among the various imperfections, fine roughness surface irregularities skin firmness brightness/discoloration cutaneous hydration were those with the greatest response to therapy. The clinical data showed that the medical device Neofound is effective and safe to treat various skin signs of chrono and photoaging thanks to its ability to protect tissues from oxidative stress and hydrate the skin.

Keywords: Neofound; amino acids vitamins; antioxidants; facial aging; mesotherapy; non-reticulated hyaluronic acid.

Publication types

  • Clinical Trial

MeSH terms

  • Aging
  • Humans
  • Hyaluronic Acid
  • Italy
  • Mesotherapy*
  • Rejuvenation
  • Skin Aging*

Substances

  • Hyaluronic Acid