A novel class of tsRNA signatures as biomarkers for diagnosis and prognosis of pancreatic cancer

Fangfang Jin; Liuqing Yang; Weixiang Wang; Na Yuan; Shoubin Zhan; Ping Yang; Xi Chen; Tonghui Ma; Yanbo Wang

doi:10.1186/s12943-021-01389-5

A novel class of tsRNA signatures as biomarkers for diagnosis and prognosis of pancreatic cancer

Mol Cancer. 2021 Jul 17;20(1):95. doi: 10.1186/s12943-021-01389-5.

Authors

Fangfang Jin^#¹, Liuqing Yang^#², Weixiang Wang^#³, Na Yuan¹, Shoubin Zhan³, Ping Yang⁴, Xi Chen⁵, Tonghui Ma⁶, Yanbo Wang⁷

Affiliations

¹ School of Medicine & Holistic Integrative Medicine, Nanjing University of Chinese Medicine, Nanjing, 210023, China.
² Department of Infectious Diseases, Department of Gastrointestinal Surgery, The First People's Hospital of Lianyungang, The First Affiliated Hospital of Kangda College of Nanjing Medical University, Lianyungang, Jiangsu, China.
³ Nanjing Drum Tower Hospital Center of Molecular Diagnostic and Therapy, Chemistry and Biomedicine Innovation Center (ChemBIC), State Key Laboratory of Pharmaceutical Biotechnology and Department of Physiology, Jiangsu Engineering Research Center for MicroRNA Biology and Biotechnology, NJU Advanced Institute of Life Sciences (NAILS), School of Life Sciences, Nanjing University, Nanjing, 210023, China.
⁴ Department of Clinical Laboratory, The Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing, 210093, China.
⁵ Nanjing Drum Tower Hospital Center of Molecular Diagnostic and Therapy, Chemistry and Biomedicine Innovation Center (ChemBIC), State Key Laboratory of Pharmaceutical Biotechnology and Department of Physiology, Jiangsu Engineering Research Center for MicroRNA Biology and Biotechnology, NJU Advanced Institute of Life Sciences (NAILS), School of Life Sciences, Nanjing University, Nanjing, 210023, China. xichen@nju.edu.cn.
⁶ School of Medicine & Holistic Integrative Medicine, Nanjing University of Chinese Medicine, Nanjing, 210023, China. matonghui@njucm.edu.cn.
⁷ Nanjing Drum Tower Hospital Center of Molecular Diagnostic and Therapy, Chemistry and Biomedicine Innovation Center (ChemBIC), State Key Laboratory of Pharmaceutical Biotechnology and Department of Physiology, Jiangsu Engineering Research Center for MicroRNA Biology and Biotechnology, NJU Advanced Institute of Life Sciences (NAILS), School of Life Sciences, Nanjing University, Nanjing, 210023, China. ybwang@nju.edu.cn.

^# Contributed equally.

No abstract available

Keywords: Biomarker; Pancreatic cancer; tsRNA.

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Animals
Biomarkers, Tumor*
Circulating MicroRNA
Disease Models, Animal
Ectopic Gene Expression
Gene Expression Profiling
Heterografts
Humans
Immunohistochemistry
Mice
Pancreatic Neoplasms / blood
Pancreatic Neoplasms / diagnosis*
Pancreatic Neoplasms / genetics*
Prognosis
RNA, Small Untranslated / blood
RNA, Small Untranslated / genetics*
RNA, Transfer / blood
RNA, Transfer / genetics*
ROC Curve
Transcriptome

Substances

Biomarkers, Tumor
Circulating MicroRNA
RNA, Small Untranslated
RNA, Transfer