Updates on Lobular Neoplasms and Papillary, Adenomyoepithelial, and Fibroepithelial Lesions of the Breast

Arch Pathol Lab Med. 2022 Aug 1;146(8):930-939. doi: 10.5858/arpa.2021-0091-RA.

Abstract

Context.—: This review article is a result of the breast pathology lectures given at the Sixth Chinese American Pathologists Association annual diagnostic pathology course in October 2020 (held virtually due to COVID-19).

Objective.—: To update recent developments, in this review article, the authors wrote minireviews in the following 4 areas: lobular neoplasm, adenomyoepithelial lesions, papillary lesions, and fibroepithelial lesions.

Data sources.—: The sources include extensive literature review, personal research, and experience.

Conclusions.—: With the wide practice of screening mammography, these lesions are not uncommon in image-guided core biopsies and excisional specimens. Many recent developments have emerged in understanding these lesions. We aim to provide readers with concise updates for each of these lesions with a focus on recent updates in definitions, diagnostic criteria, management, and molecular profiles that are most relevant to the daily practice of pathology and patient management.

Publication types

  • Review

MeSH terms

  • Breast / diagnostic imaging
  • Breast / pathology
  • Breast Neoplasms* / diagnosis
  • Breast Neoplasms* / pathology
  • COVID-19*
  • Early Detection of Cancer
  • Female
  • Humans
  • Mammography
  • Precancerous Conditions* / pathology