Predictability of COVID-19-related morbidity and mortality based on model estimations to establish proactive protocols of countermeasures

Sci Rep. 2021 Jul 15;11(1):14523. doi: 10.1038/s41598-021-93932-z.

Abstract

The COVID-19 pandemic (SARS-CoV-2) has revealed the need for proactive protocols to react and act, imposing preventive and restrictive countermeasures on time in any society. The extent to which confirmed cases can predict the morbidity and mortality in a society remains an unresolved issue. The research objective is therefore to test a generic model's predictability through time, based on percentage of confirmed cases on hospitalized patients, ICU patients and deceased. This study reports the explanatory and predictive ability of COVID-19-related healthcare data, such as whether there is a spread of a contagious and virulent virus in a society, and if so, whether the morbidity and mortality can be estimated in advance in the population. The model estimations stress the implementation of a pandemic strategy containing a proactive protocol entailing what, when, where, who and how countermeasures should be in place when a virulent virus (e.g. SARS-CoV-1, SARS-CoV-2 and MERS) or pandemic strikes next time. Several lessons for the future can be learnt from the reported model estimations. One lesson is that COVID-19-related morbidity and mortality in a population is indeed predictable. Another lesson is to have a proactive protocol of countermeasures in place.

MeSH terms

  • COVID-19 / epidemiology*
  • COVID-19 / mortality*
  • Forecasting / methods*
  • Hospitalization / statistics & numerical data
  • Hospitalization / trends
  • Humans
  • Intensive Care Units / statistics & numerical data
  • Intensive Care Units / trends
  • Models, Statistical
  • Morbidity
  • Pandemics
  • Public Health / statistics & numerical data
  • Public Policy / trends
  • SARS-CoV-2 / isolation & purification