A holographic imaging system based on reconfigurable time-frequency division multiplexing metasurface (RTFDMM) has been designed, in an attempt to address the problems of insufficient flexibility, low signal-to-noise ratio (SNR), and low data of traditional metasurface imaging devices. The modified Gerchberg-Saxton (MGS) algorithm in the front end of this system has been proposed to calculate the phase distribution required by the diffraction metasurface at the back end. The 1-bit low loss reconfigurable metasurface has been desiged in X-band. To obtain the best imaging results, the appropriate ranges of imazging distance, pixel size and resolution ratio are given by adjusting the phase distribution of metasurface. Based on the MGS algorithm and the 1-bit metasurface, the high-quality imaging system has been successfully established through the time-frequency division multiplexing (TFDM) technology. The high SNR imaging can be generated with the expansion of the time domain, while the high data imaging can be yielded with the quantization of the frequency domain. The proof-of-concept has demonstrated that the high data, high SNR, and high flexibility of the RTFDMM are critical technologies for the advancement of detection imaging equipment. Therefore, there are great possibilities for RTFDMM holographic imaging system to be applied in the intelligent detection platform in the future.