Malignant gliomas with H3F3A G34R mutation or MYCN amplification in pediatric patients with Li Fraumeni syndrome

Acta Neuropathol. 2021 Sep;142(3):591-593. doi: 10.1007/s00401-021-02346-8. Epub 2021 Jul 15.
No abstract available

Publication types

  • Case Reports
  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Brain Neoplasms / genetics*
  • Brain Neoplasms / pathology
  • Gene Amplification
  • Germ-Line Mutation
  • Glioma / genetics*
  • Glioma / pathology
  • Histones / genetics*
  • Humans
  • Li-Fraumeni Syndrome / genetics*
  • Male
  • Mutation / genetics*
  • N-Myc Proto-Oncogene Protein / genetics*

Substances

  • H3-3A protein, human
  • Histones
  • MYCN protein, human
  • N-Myc Proto-Oncogene Protein