Treatment with Radiopharmaceuticals and Radionuclides in Breast Cancer: Current Options

Eur J Breast Health. 2021 Jun 24;17(3):214-219. doi: 10.4274/ejbh.galenos.2021.2021-3-4. eCollection 2021 Jul.

Abstract

Radiopharmaceutical therapy (RPT) is an effective and safe treatment for many types of cancer. RPT acts by binding radioactive atoms to tumor-associated antigens, monoclonal antibodies, nanoparticles, peptides, and small molecules. These treatments ensure that a concentrated dose is delivered to the targeted tumor tissue while preserving the normal tissues surrounding the tumor. Given these features, RPT is superior to traditional methods. This review article aimed to performa comprehensive review and evaluation of the potential of radionuclides and radiopharmaceuticals used in breast cancer treatment in preclinical studies conducted in the last five years.

Keywords: Breast cancer; radioisotopes; radionuclide therapy; radiopharmaceuticals.

Publication types

  • Review