Metastatic Thyroid Osteosarcoma With Concomitant Multifocal Papillary Carcinoma Presenting as a Collision Tumor

Nektarios Koufopoulos; Andriani Zacharatou; Alina-Roxani Gouloumis; Nikolaos Papadimitriou; Periklis Tomos; Periklis G Foukas; Ioannis G Panayiotides

doi:10.7759/cureus.15425

Metastatic Thyroid Osteosarcoma With Concomitant Multifocal Papillary Carcinoma Presenting as a Collision Tumor

Cureus. 2021 Jun 3;13(6):e15425. doi: 10.7759/cureus.15425. eCollection 2021 Jun.

Authors

Nektarios Koufopoulos¹, Andriani Zacharatou¹, Alina-Roxani Gouloumis¹, Nikolaos Papadimitriou², Periklis Tomos³, Periklis G Foukas¹, Ioannis G Panayiotides¹

Affiliations

¹ 2nd Department of Pathology, National and Kapodistrian University of Athens, "Attikon" University Hospital, Athens, GRC.
² 2nd Department of Ear, Nose, Throat (ENT), National and Kapodistrian University of Athens, "Attikon" University Hospital, Athens, GRC.
³ Department of Thoracic Surgery, National and Kapodistrian University of Athens, "Attikon" University Hospital, Athens, GRC.

Abstract

Metastatic involvement of the thyroid occurs rarely, by either hematogenous spread or direct extension from adjacent organs. The most frequent metastatic tumors are clear cell, renal cell, lung, breast, and squamous cell carcinoma. The occurrence of osteosarcoma and papillary thyroid carcinoma in the same patient is rare, with only a few reported cases in the literature. On the other hand, only one case of osteosarcoma thyroid metastasis has so far been reported. We herewith present another case with metastatic osteosarcoma and multifocal papillary thyroid carcinoma presenting as a collision tumor and review the relevant literature.

Keywords: collision tumor; metastasis; osteosarcoma; papillary carcinoma; thyroid.

Publication types

Case Reports