An Adolescent With Neurobrucellosis Caused by Brucella abortus Cattle Vaccine Strain RB51

Pediatr Infect Dis J. 2021 Sep 1;40(9):e353-e355. doi: 10.1097/INF.0000000000003200.

Abstract

We present the case of an 18-year-old female with a 1-month history of fever, headache, and double vision, whose examination revealed papilledema and cranial nerve VI palsy. Blood cultures grew Brucella abortus cattle vaccine strain RB51, which is inherently resistant to rifampin. We discuss the management of the first known case of neurobrucellosis by this strain.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Animals
  • Anti-Bacterial Agents / pharmacology
  • Anti-Bacterial Agents / therapeutic use
  • Antibodies, Bacterial / blood
  • Brain / diagnostic imaging
  • Brain / microbiology
  • Brain / pathology
  • Brucella Vaccine / analysis*
  • Brucella abortus / drug effects
  • Brucella abortus / isolation & purification
  • Brucella abortus / pathogenicity*
  • Brucellosis / cerebrospinal fluid*
  • Brucellosis / diagnostic imaging*
  • Brucellosis / drug therapy
  • Brucellosis / microbiology
  • Cattle
  • Central Nervous System Infections / diagnostic imaging*
  • Central Nervous System Infections / microbiology
  • Female
  • Humans
  • Magnetic Resonance Imaging
  • Neuroimaging
  • Rifampin / pharmacology

Substances

  • Anti-Bacterial Agents
  • Antibodies, Bacterial
  • Brucella Vaccine
  • Rifampin