Objective: To observe the effect of acupoint thread-embedding on visual acuity and morphology of retina in children with refractive amblyopia.
Methods: A total of 60 children with refractive amblyopia were randomized into an observation group (30 cases, 2 cases dropped off) and a control group (30 cases, 1 case dropped off). In the control group, comprehensive therapy of eye covering of intact side and family refined performance was adopted. On the basis of the treatment in the control group, acupoint thread-embedding was applied at Ganshu (BL 18), Pishu (BL 20), Shenshu (BL 23), Zusanli (ST 36), Guangming (GB 37) in the observation group, once every 2 weeks. The treatment for 2 months was required in the both groups. The corrected vision and the variations of macular thickness of retina and average thickness of retinal nerve fiber layer (RNFL) before and after treatment were observed, and the therapeutic efficacy was evaluated in the both groups.
Results: After treatment, the corrected vision was increased compared before treatment in the both groups (P<0.05), and the improvement of corrected vision in the observation group was superior to that in the control group (P<0.05); the macular thickness of retina and the average thickness of RNFL were thinner compared before treatment in the both groups (P<0.05), and the macular thickness of retina and the average thickness of RNFL in the observation group were thinner than those in the control group (P<0.05). The total effective rate was 92.9% (26/28) in the observation group, which was superior to 79.3% (23/29) in the control group (P<0.05).
Conclusion: Acupoint thread-embedding can effectively increase the corrected vision in children with refractive amblyopia, and has improvement in retina morphological damage to a certain extent.
目的：观察穴位埋线对屈光性弱视患儿视力与视网膜形态的影响。方法：将60例单眼屈光性弱视患儿随机分为观察组（30例，脱落2例）和对照组（30例，脱落1例）。对照组予遮盖健眼及家庭精细作业的综合疗法；观察组在对照组基础上予穴位埋线治疗，穴取肝俞、脾俞、肾俞、足三里、光明，每2周1次，均治疗2个月。分别于治疗前后观察两组患儿矫正视力及视网膜黄斑厚度、神经纤维层（RNFL）平均厚度改变，并评定临床疗效。结果：治疗后，两组患儿矫正视力均较治疗前提高（P<0.05），且观察组矫正视力改善程度优于对照组（P<0.05）；视网膜黄斑厚度、RNLF平均厚度均较治疗前变薄（P<0.05），且观察组视网膜黄斑厚度、RNLF平均厚度均薄于对照组（P<0.05）。观察组总有效率为92.9%（26/28），高于对照组的79.3%（23/29，P<0.05）。结论：穴位埋线能有效提高屈光性弱视患儿的矫正视力，并对视网膜形态损害具有一定的改善作用。.
Keywords: acupoint thread-embedding; corrected vision; covering therapy; family refined performance therapy; morphology of retina; randomized controlled trial (RCT); refractive amblyopia.