Porcine enteric coronaviruses: an updated overview of the pathogenesis, prevalence, and diagnosis

Vet Res Commun. 2021 Sep;45(2-3):75-86. doi: 10.1007/s11259-021-09808-0. Epub 2021 Jul 12.

Abstract

The recent prevalence of coronavirus (CoV) poses a serious threat to animal and human health. Currently, porcine enteric coronaviruses (PECs), including the transmissible gastroenteritis virus (TGEV), the novel emerging swine acute diarrhoea syndrome coronavirus (SADS-CoV), porcine delta coronavirus (PDCoV), and re-emerging porcine epidemic diarrhoea virus (PEDV), which infect pigs of different ages, have caused more frequent occurrences of diarrhoea, vomiting, and dehydration with high morbidity and mortality in piglets. PECs have the potential for cross-species transmission and are causing huge economic losses in the pig industry in China and the world, which therefore needs to be urgently addressed. Accordingly, this article summarises the pathogenicity, prevalence, and diagnostic methods of PECs and provides an important reference for their improved diagnosis, prevention, and control.

Keywords: Porcine delta coronavirus; Porcine enteric coronavirus; Porcine epidemic diarrhoea virus; Swine acute diarrhoea syndrome coronavirus; Transmissible gastroenteritis virus.

Publication types

  • Review

MeSH terms

  • Alphacoronavirus / genetics
  • Alphacoronavirus / pathogenicity
  • Animals
  • China / epidemiology
  • Coronavirus Infections / diagnosis
  • Coronavirus Infections / epidemiology
  • Coronavirus Infections / prevention & control
  • Coronavirus Infections / veterinary*
  • Deltacoronavirus / genetics
  • Deltacoronavirus / pathogenicity
  • Humans
  • Porcine epidemic diarrhea virus / genetics
  • Porcine epidemic diarrhea virus / pathogenicity
  • Prevalence
  • Swine
  • Swine Diseases / diagnosis
  • Swine Diseases / epidemiology
  • Swine Diseases / prevention & control
  • Swine Diseases / virology*
  • Transmissible gastroenteritis virus / genetics
  • Transmissible gastroenteritis virus / pathogenicity

Supplementary concepts

  • Porcine coronavirus HKU15
  • Swine acute diarrhea syndrome coronavirus