Metabolic surgery in China: present and future

Yinfang Tu; Yuqian Bao; Pin Zhang

doi:10.1093/jmcb/mjab039

Metabolic surgery in China: present and future

J Mol Cell Biol. 2021 Jul 7;13(8):594-609. doi: 10.1093/jmcb/mjab039. Online ahead of print.

Authors

Yinfang Tu¹, Yuqian Bao^{1

2}, Pin Zhang³

Affiliations

¹ Department of Endocrinology and Metabolism, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai Diabetes Institute, Shanghai Clinical Center of Diabetes, Shanghai Key Laboratory of Diabetes Mellitus, Shanghai Key Clinical Center for Metabolic Disease, Shanghai 200233, China.
² Department of Endocrinology and Metabolism, Jinshan District Central Hospital of Shanghai Sixth People's Hospital, Shanghai 201599, China.
³ Department of Bariatric & Metabolic Surgery, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai 200233, China.

Abstract

Obesity and its related complications comprise a serious public health problem worldwide, and obesity is increasing in China. Metabolic surgery is a new type of treatment with unique advantages in weight loss and obesity-related metabolic complications. The pathogenesis of obesity is complex and not yet fully understood. Here, we review the current efficacy and safety of metabolic surgery, as well as recent progress in mechanistic studies and surgical procedures in China. The exciting and rapid advances in this field provide new opportunities for patients with obesity and strike a balance between long-term effectiveness and safety.