High consumption of Nickel-containing foods and IBS-like disorders: late events in a gluten-free diet

Ecotoxicol Environ Saf. 2021 Oct 1:222:112492. doi: 10.1016/j.ecoenv.2021.112492. Epub 2021 Jul 6.

Abstract

As reported in the recent literature, Nickel has become an important part of our daily life since the last decades. We can find it in skincare products, occupational exposures and foods. Only recently, research has started to show a link between Nickel and many health disorders, including adverse reactions to food containing nickel. Nowadays, the relationship between nickel-containing foods and well-being is becoming a topic of growing interest in clinical practice and will play an even larger role in the future. The use of foods with a high nickel content, largely present in a gluten free diet, could explain the lack of clinical remission in celiac patients and dispel a diagnosis of refractory celiac disease.

Keywords: Allergic Contact Dermatitis (ACD); Allergic Contact Mucositis (ACM); Celiac disease; Irritable Bowel Syndrome (IBS); Nickel.

Publication types

  • Letter

MeSH terms

  • Celiac Disease*
  • Diet, Gluten-Free
  • Food
  • Humans
  • Irritable Bowel Syndrome*
  • Nickel / toxicity

Substances

  • Nickel