Knowledge-based radiation treatment planning: A data-driven method survey

J Appl Clin Med Phys. 2021 Aug;22(8):16-44. doi: 10.1002/acm2.13337. Epub 2021 Jul 7.

Abstract

This paper surveys the data-driven dose prediction methods investigated for knowledge-based planning (KBP) in the last decade. These methods were classified into two major categories-traditional KBP methods and deep-learning (DL) methods-according to their techniques of utilizing previous knowledge. Traditional KBP methods include studies that require geometric or anatomical features to either find the best-matched case(s) from a repository of prior treatment plans or to build dose prediction models. DL methods include studies that train neural networks to make dose predictions. A comprehensive review of each category is presented, highlighting key features, methods, and their advancements over the years. We separated the cited works according to the framework and cancer site in each category. Finally, we briefly discuss the performance of both traditional KBP methods and DL methods, then discuss future trends of both data-driven KBP methods to dose prediction.

Keywords: data-driven methods; deep learning; knowledge-based planning; machine learning; radiation dose prediction methods; radiotherapy treatment planning.

Publication types

  • Review

MeSH terms

  • Humans
  • Knowledge Bases
  • Radiotherapy Dosage
  • Radiotherapy Planning, Computer-Assisted*
  • Radiotherapy, Intensity-Modulated*