Influence of concomitant injuries on post-concussion symptoms after a mild traumatic brain injury - a prospective multicentre cohort study

Brain Inj. 2021 Jul 29;35(9):1028-1034. doi: 10.1080/02699052.2021.1945145. Epub 2021 Jul 5.

Abstract

Objectives: To compare post-concussion symptoms (PCS) and return to normal activities between mild Traumatic Brain Injury (mTBI) patients with or without concomitant injuries at 7-and 90 days post-mTBI.Methods: Design: Sub-analysis of a multicentre prospective cohort study.

Participants and setting: patients with mTBI from 7 Canadian Emergency Departments.

Procedure: Research assistants conducted telephone follow-ups using the Rivermead Postconcussion Symptoms Questionnaire (RPQ) at 7-, 30- and 90 days post-mTBI.

Main outcome: Presence of PCS (RPQ: ≥3 symptoms) at 90 days.

Secondary outcomes: RPQ score ≥21, prevalence of individual RPQ symptoms and patients' return to normal activities, at 7- and 90-days. Adjusted risk ratios (RR) were calculated.Results: 1725 mTBI patients were included and 1055 (61.1%) had concomitant injuries. Patients with concomitant injuries were at higher risk of having ≥3 symptoms on the RPQ (RR:1.26 [95% CI 1.01-1.58]) at 90 days. They were also at higher risk of experiencing specific symptoms (dizziness, fatigue, headaches and taking longer to think) and of non-return to their normal activities (RR:2.11 [95% CI 1.30-3.45]).Conclusion: Patients with concomitant injuries have slightly more PCS and seemed to be at higher risk of non-return to their normal activities 90 days, compared to patients without concomitant injuries.

Keywords: Brain injuries; concomitant injuries; post-concussion symptoms; rivermead post-concussion symptoms questionnaire.

Publication types

  • Multicenter Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Brain Concussion* / complications
  • Brain Concussion* / epidemiology
  • Canada / epidemiology
  • Emergency Service, Hospital
  • Humans
  • Post-Concussion Syndrome* / epidemiology
  • Post-Concussion Syndrome* / etiology
  • Prospective Studies

Grants and funding