Prolonged survival after laser interstitial thermal therapy in glioblastoma

A Basit Khan; Carlos Kamiya Matsuoka; Sungho Lee; Maryam Rahman; Ganesh Rao

doi:10.25259/SNI_174_2021

Prolonged survival after laser interstitial thermal therapy in glioblastoma

Surg Neurol Int. 2021 May 17:12:228. doi: 10.25259/SNI_174_2021. eCollection 2021.

Authors

A Basit Khan¹, Carlos Kamiya Matsuoka², Sungho Lee¹, Maryam Rahman³, Ganesh Rao¹

Affiliations

¹ Department of Neurosurgery, Baylor College of Medicine, Houston, Texas, United States.
² Department of Neuro-Oncology, MD Anderson Cancer Center, Houston, Texas, United States.
³ Department of Neurosurgery, University of Florida, Gainesville, Florida, United States.

Abstract

Background: Glioblastoma (GBM) is the most common primary malignant brain tumor in adults. Management includes surgical resection followed by chemoradiation, and prognosis remains poor. Surgical resection is not possible for some deep-seated or eloquent tumors. Laser interstitial thermal therapy (LITT) has emerged as a new, minimally invasive surgical option for deep-seated GBM.

Case description: We report a case of newly diagnosed thalamic GBM managed with LITT followed by radiation and chemotherapy.

Conclusion: The patient remains well at 50-month post-LITT, indicating a potentially unique durability of LITT treatment in GBM.

Keywords: Glioblastoma; Laser interstitial thermal therapy; Survival.

Publication types

Case Reports