Reversibility of oxalate nephropathy in a kidney transplant recipient with prior gastric bypass surgery

Clin Kidney J. 2021 Jan 4;14(5):1478-1480. doi: 10.1093/ckj/sfaa254. eCollection 2021 May.

Abstract

Bariatric surgery is an acknowledged treatment for obesity and related comorbidities with beneficial effects on kidney function. However, bariatric surgery can also lead to secondary hyperoxaluria and oxalate nephropathy, resulting in end-stage kidney disease in both native and transplanted kidneys. We present a 66-year-old man who was in need of dialysis 3 months after kidney transplantation due to recurrent oxalate nephropathy. Intensified haemodialysis together with increased liquid intake, dietary restrictions of oxalate and fat and supplementation with calcium citrate and a bile acid binder were applied. Graft function improved and the patient did not require dialysis during the following 8 months.

Keywords: Roux en-Y gastric bypass; bile acid binders; gastric bypass; haemodialysis; hyperoxaluria; kidney transplantation; oxalate nephropathy; secondary oxalosis.

Publication types

  • Case Reports