Sunlight-driven rapid and facile synthesis of Silver nanoparticles using Allium ampeloprasum extract with enhanced antioxidant and antifungal activity

V Uma Maheshwari Nallal; K Prabha; I VethaPotheher; Balasubramani Ravindran; Alaa Baazeem; Soon Woong Chang; Gloria Aderonke Otunola; M Razia

doi:10.1016/j.sjbs.2021.05.001

Sunlight-driven rapid and facile synthesis of Silver nanoparticles using Allium ampeloprasum extract with enhanced antioxidant and antifungal activity

Saudi J Biol Sci. 2021 Jul;28(7):3660-3668. doi: 10.1016/j.sjbs.2021.05.001. Epub 2021 May 13.

Authors

V Uma Maheshwari Nallal¹, K Prabha², I VethaPotheher³, Balasubramani Ravindran⁴, Alaa Baazeem⁵, Soon Woong Chang⁴, Gloria Aderonke Otunola⁶, M Razia¹

Affiliations

¹ Department of Biotechnology, Mother Teresa Women's University, Kodaikanal, Tamil Nadu, India.
² Department of Physics, Mother Teresa Women's University, Kodaikanal, Tamil Nadu, India.
³ Department of Physics, University College of Engineering, Bharathidasan Institute of Technology Campus, Anna University, Tiruchirapalli, Tamil Nadu, India.
⁴ Department of Environmental Energy and Engineering, Kyonggi University, Youngtong - Gu, Suwon 16227, Republic of Korea.
⁵ Department of Biology, College of Science, Taif University, P.O. Box 11099, Taif 21944, Saudi Arabia.
⁶ Medicinal Plants and Economic Development (MPED) Research Center, Department of Botany, University of Fort Hare, Alice 5700, South Africa.

Abstract

Green nanotechnology has acquired immense demand due to its cost-effective, eco-friendly and benevolent approach for the synthesis of nanoparticles. Among the biological methods, plants aid as a significant green resource for synthesizing nanoparticles that are safe and non-toxic for human use. In the present investigation, Silver nanoparticles (AgNPs) were synthesized using bulbs extract of Allium ampeloprasum under the influence of sunlight irradiation and characterized using different techniques. Distinct in-vitro assays were performed to test the antioxidant and anticandida potential of the synthesized AgNPs. Results suggested the efficient and rapid sunlight-driven synthesis of AgNPs using A. ampeloprasum extract. UV-Vis spectrum showed absorption peak at 446 nm which confirmed the formation of AgNPs. FTIR analysis suggested the presence of functional groups associated with flavonoids and sulfur compounds in A. ampeloprasum extract. The synthesized AgNPs showed Face Centred Cubic (FCC) structure with an average size of 35 nm. Spherical, quasi spherical, triangular and ellipsoidal morphology of the NPs were observed from the TEM micrograph. The synthesized AgNPs showed pronounced free radical scavenging potential for DPPH, ABTS∙+ and H₂O₂ radicals. The anticandida potency of the synthesized AgNPs was observed as follows: C. albicans ≥ C. tropicalis ≥ C. glabrata ≥ C. parapsilosis ≥ C. krusei. Results showed that sunlight driven nanoparticle synthesis of AgNPs is rapid, facile and exhibit enhanced antioxidant and antifungal activity.

Keywords: A. ampeloprasum; AgNPs; Antifungal activity; Antioxidant activity; Sunlight.