Patient-Reported Outcomes in Lupus

Narender Annapureddy; Meenakshi Jolly

doi:10.1016/j.rdc.2021.04.004

Patient-Reported Outcomes in Lupus

Rheum Dis Clin North Am. 2021 Aug;47(3):351-378. doi: 10.1016/j.rdc.2021.04.004. Epub 2021 Jun 16.

Authors

Narender Annapureddy¹, Meenakshi Jolly²

Affiliations

¹ Department of Medicine, Vanderbilt University, 1160 21st Avenue, Suite T3113 MCN, Nashville, TN 37232, USA.
² Department of Medicine, Rush University, 1611 West Harrison Street, Suite 510, Chicago, IL 60615, USA. Electronic address: Meenakshi_Jolly@Rush.edu.

PMID: 34215368
DOI: 10.1016/j.rdc.2021.04.004

Abstract

Patient-reported outcome (PRO) was identified as a core systemic lupus erythematosus (SLE) outcome in 1999. More than 20 years later, however, generic PRO measures evaluating impact in SLE are used mainly for research. Generic and disease-targeted PRO tools have unique advantages. Significant progress in identification of patient disease-relevant PRO concepts and development of new PRO tools for SLE has occurred over the past 20 years. Further research needs to focus on responsiveness and minimally important differences of existing, promising PRO tools to facilitate their use in SLE patient care and research.

Keywords: Patient-reported outcome (PRO); Quality of life (QOL); Systemic lupus erythematosus (SLE).

Publication types

Review

MeSH terms

Humans
Lupus Erythematosus, Systemic* / diagnosis
Lupus Erythematosus, Systemic* / drug therapy
Lupus Erythematosus, Systemic* / epidemiology
Patient Reported Outcome Measures
Quality of Life*