Ending the Neglect of Treatable Bacterial Zoonoses Responsible for Non-Malaria Fevers

Yale J Biol Med. 2021 Jun 30;94(2):351-360. eCollection 2021 Jun.

Abstract

Bacterial zoonotic diseases such as leptospirosis, Q fever, melioidosis, spotted fever group rickettsioses, and brucellosis are increasingly recognized causes of non-malaria acute fevers. However, though readily treatable with antibiotics, these diseases are commonly misdiagnosed resulting in poor outcomes in patients. There is a considerable deficit in the understanding of basic aspects of the epidemiology of these neglected diseases and diagnostic tests for these zoonotic bacterial pathogens are not always available in resource-poor settings. Raising awareness about these emerging bacterial zoonoses is directly beneficial to the patients by allowing a test-and-treat approach and is essential to control these life-threatening diseases.

Keywords: antibiotics; leptospirosis; neglected tropical diseases; tropical countries.

Publication types

  • Review

MeSH terms

  • Animals
  • Bacteria
  • Bacterial Zoonoses
  • Brucellosis*
  • Fever
  • Humans
  • Leptospirosis*