Central Sleep Apnea

Clin Geriatr Med. 2021 Aug;37(3):469-481. doi: 10.1016/j.cger.2021.04.009. Epub 2021 Jun 4.

Abstract

Central sleep apnea (CSA) is characterized by intermittent repetitive cessation and/or decreased breathing without effort caused by an abnormal ventilatory drive. Although less prevalent than obstructive sleep apnea, it is frequently encountered. CSA can be primary (idiopathic) or secondary in association with Cheyne-Stokes respiration, drug-induced, medical conditions such as chronic renal failure, or high-altitude periodic breathing. Risk factors have been proposed, including gender, age, heart failure, opioid use, stroke, and other chronic medical conditions. This article discusses the prevalence of CSA in the general population and within each of these at-risk populations, and clinical presentation, diagnostic methods, and treatment.

Keywords: Central sleep apnea; Diagnosis; Epidemiology; Treatment.

Publication types

  • Review

MeSH terms

  • Aged
  • Cheyne-Stokes Respiration / physiopathology*
  • Continuous Positive Airway Pressure / adverse effects*
  • Humans
  • Polysomnography
  • Prevalence
  • Quality of Life
  • Sleep / physiology*
  • Sleep Apnea, Central / diagnosis*
  • Sleep Apnea, Central / epidemiology
  • Sleep Apnea, Central / therapy*