Circadian Blood Pressure Rhythm in Cardiovascular and Renal Health and Disease

Biomolecules. 2021 Jun 11;11(6):868. doi: 10.3390/biom11060868.

Abstract

Blood pressure (BP) follows a circadian rhythm, it increases on waking in the morning and decreases during sleeping at night. Disruption of the circadian BP rhythm has been reported to be associated with worsened cardiovascular and renal outcomes, however the underlying molecular mechanisms are still not clear. In this review, we briefly summarized the current understanding of the circadian BP regulation and provided therapeutic overview of the relationship between circadian BP rhythm and cardiovascular and renal health and disease.

Keywords: blood pressure; cardiovascular; circadian rhythm; renal.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Blood Pressure / physiology*
  • Cardiovascular Diseases / metabolism
  • Cardiovascular Diseases / physiopathology*
  • Cardiovascular System / physiopathology
  • China
  • Circadian Rhythm / physiology*
  • Humans
  • Hypertension / physiopathology
  • Kidney / physiopathology
  • Kidney Diseases / metabolism
  • Kidney Diseases / physiopathology*