The First Data on the Complete Genome of a Tetrodotoxin-Producing Bacterium

Toxins (Basel). 2021 Jun 9;13(6):410. doi: 10.3390/toxins13060410.

Abstract

Tetrodotoxin (TTX)-producing bacteria have attracted great interest as a model system for study of the TTX biosynthetic route. Here, we report the complete genome of the TTX-producing bacterium Bacillus sp. 1839. The genome of the strain Bacillus sp. 1839, previously isolated from the TTX-bearing marine ribbon worm Cephalothrix cf. simula, was obtained using second generation Illumina and third generation nanopore sequencing technologies. Phylogenetic analysis has classified this strain as Cytobacillus gottheilii.

Keywords: TTX-producing bacteria; genome; tetrodotoxin (TTX).

MeSH terms

  • Bacillus / genetics*
  • Bacillus / metabolism*
  • Genome, Bacterial*
  • Phylogeny
  • Tetrodotoxin / biosynthesis*

Substances

  • Tetrodotoxin