Human Leucocyte Antigen alleles associated with asparaginase hypersensitivity in childhood Acute Lymphoblastic Leukemia patients treated with Pegylated asparaginase within Dana Farber Cancer Institute treatment protocols

Leuk Res. 2021 Oct:109:106650. doi: 10.1016/j.leukres.2021.106650. Epub 2021 Jun 23.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Antineoplastic Agents / adverse effects*
  • Asparaginase / adverse effects*
  • Canada / epidemiology
  • Child
  • Drug Hypersensitivity / epidemiology*
  • Drug Hypersensitivity / etiology
  • Drug Hypersensitivity / pathology
  • Female
  • HLA Antigens / genetics
  • HLA Antigens / immunology*
  • Humans
  • Male
  • Polyethylene Glycols / adverse effects*
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma / drug therapy*
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma / pathology
  • Prognosis

Substances

  • Antineoplastic Agents
  • HLA Antigens
  • Polyethylene Glycols
  • pegaspargase
  • Asparaginase