IL4-STAT6 signaling induces CD20 in chronic lymphocytic leukemia and this axis is repressed by PI3Kδ inhibitor idelalisib

Haematologica. 2021 Nov 1;106(11):2995-2999. doi: 10.3324/haematol.2021.278644.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Antigens, CD20 / metabolism*
  • Antineoplastic Agents* / therapeutic use
  • Humans
  • Interleukin-4
  • Leukemia, Lymphocytic, Chronic, B-Cell* / drug therapy
  • Purines / pharmacology
  • Purines / therapeutic use
  • Quinazolinones / pharmacology
  • Quinazolinones / therapeutic use
  • STAT6 Transcription Factor

Substances

  • Antigens, CD20
  • Antineoplastic Agents
  • Purines
  • Quinazolinones
  • STAT6 Transcription Factor
  • STAT6 protein, human
  • Interleukin-4
  • idelalisib