2D vs 3D laparoscopic right colectomy: A propensity score-matching comparison of personal experience with systematic review and meta-analysis

Gianluca Costa; Pietro Fransvea; Luca Lepre; Fabio Rondelli; Alessandro Costa; Michela Campanelli; Giorgio Lisi; Maria Rosaria Mastrangeli; Giovanni Guglielmo Laracca; Giovanni Maria Garbarino; Graziano Ceccarelli

doi:10.4240/wjgs.v13.i6.597

2D vs 3D laparoscopic right colectomy: A propensity score-matching comparison of personal experience with systematic review and meta-analysis

World J Gastrointest Surg. 2021 Jun 27;13(6):597-619. doi: 10.4240/wjgs.v13.i6.597.

Affiliations

¹ Surgery Center, Campus Bio-Medico, Rome 00128, Italy.
² Department of Emergency and Trauma Surgery, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome 00168, Italy.
³ General Surgery Unit, Santo Spirito in Sassia Hospital, Rome 00193, Italy.
⁴ Department of Surgical Science, University of Perugia, Santa Maria Teaching Hospital, Terni 05100, Italy.
⁵ Catholic University "Our Lady of Good Council" School of Medicine, Tirane 1023, Albania.
⁶ Department of Emergency Surgery, Tor Vergata University Hospital, Rome 00133, Italy.
⁷ Department of General Surgery, Sant'Eugenio Hospital, Rome 00144, Italy. giolimas06@yahoo.it.
⁸ Department of General Surgery, Sant'Eugenio Hospital, Rome 00144, Italy.
⁹ Department of Medical Surgical Science and Translational Medicine, Sapienza University of Rome, Sant'Andrea Hospital, Rome 00189, Italy.
¹⁰ General Surgery Unit, San Giovanni Battista Hospital, Foligno 06034, Italy.

Abstract

Background: The benefits of laparoscopic approach for right colectomy have been well established. However, the technical difficulty to construct the intra-corporeal anastomosis is still cumbersome.

Aim: To analyze the results of 3D and 2D laparoscopic right colectomy and to compare it to the published series through a systematic review and meta-analysis.

Methods: A retrospective study with propensity score matching analysis of patients undergoing laparoscopic right colectomy at Umbria2 Hospitals from January 2014 to March 2020 was performed. A systematic review was accomplished comparing 2D and 3D right colectomy.

Results: In the personal series 47 patients of the 2D group were matched to 47 patients of the 3D group. The 3D group showed a favorable trend in terms of mean operative time (170.7 ± 32.9 min vs 183.8 ± 35.4 min; P = 0.053) and a significant lower anastomotic time (16.9 ± 2.3 min vs 19.6 ± 2.9 min, P < 0.001). The complete mesocolic excision (CME) subgroups analysis showed a shorter anastomotic time (16.5 ± 1.8 min vs 19.9 ± 3.0 min; P < 0.001) and operative time (175.0 ± 38.5 min vs 193.7 ± 37.1 min; P = 0.063) in the 3D group. Six studies and our series were included in the meta-analysis with 551 patients (2D group: 291; 3D group: 260).The pooled analysis demonstrated a significant difference in favour of the 3D group regarding the operative time (P < 0.001) and the anastomotic time (P < 0.001) while no differences were identified between groups in terms of blood loss (P = 0.827), LNH yield (P = 0.243), time to first flatus (P = 0.333), postoperative complications (P = 0.718) and length of stay (P = 0.835).

Conclusion: The meta-analysis results showed that 3D laparoscopic right colectomy shortens operative and anastomotic time without affecting the standard lymphadenectomy. In our series, the advantage of the 3D system becomes evident when CME and/or more complex associated procedure are requested significantly reducing both the total operative and the anastomotic time.

Keywords: Colon cancer; Complete mesocolic excision; Laparoscopy; Right colectomy; Three-dimensional; Two-dimensional.