An Effective Method for Detecting and Classifying Diabetic Retinopathy Lesions Based on Deep Learning

Comput Math Methods Med. 2021 May 31:2021:9928899. doi: 10.1155/2021/9928899. eCollection 2021.

Abstract

Diabetic retinopathy occurs as a result of the harmful effects of diabetes on the eyes. Diabetic retinopathy is also a disease that should be diagnosed early. If not treated early, vision loss may occur. It is estimated that one third of more than half a million diabetic patients will have diabetic retinopathy by the 22nd century. Many effective methods have been proposed for disease detection with deep learning. In this study, unlike other studies, a deep learning-based method has been proposed in which diabetic retinopathy lesions are detected automatically and independently of datasets, and the detected lesions are classified. In the first stage of the proposed method, a data pool is created by collecting diabetic retinopathy data from different datasets. With Faster RCNN, lesions are detected, and the region of interests are marked. The images obtained in the second stage are classified using the transfer learning and attention mechanism. The method tested in Kaggle and MESSIDOR datasets reached 99.1% and 100% ACC and 99.9% and 100% AUC, respectively. When the obtained results are compared with other results in the literature, it is seen that more successful results are obtained.

MeSH terms

  • Computational Biology
  • Databases, Factual
  • Deep Learning*
  • Diabetic Retinopathy / classification*
  • Diabetic Retinopathy / diagnostic imaging*
  • Diagnosis, Computer-Assisted / methods
  • Fundus Oculi
  • Humans
  • Image Interpretation, Computer-Assisted
  • Neural Networks, Computer
  • Ophthalmoscopy
  • Optic Disk / diagnostic imaging
  • ROC Curve