This article explores the asymptotic stabilization criteria of the uncertain nonlinear time-delay system subject to actuator saturation. A switched integral-based event-triggered scheme (IETS) is established to reduce the redundant data transmission over the networks. The switched IETS condition uses the integration of system states over a time period in the past. A fixed waiting time is included to avoid the Zeno behavior. In order to estimate a larger domain of attraction, a delay-dependent polytopic representation method is presented to deal with the effects of actuator saturation in the proposed model. A new series of less conservative linear matrix inequalities (LMIs) is proposed on the basis of delay-dependent Lyapunov-Krasovskii functional (LKF) to ensure the stability of nonlinear time-delay system subject to actuator saturation using the proposed IETS. Numerical examples are used to confirm the effectiveness and advantages of the proposed IETS approach.