H3K4me3 histone modification in baculovirus-infected silkworm cells

Virus Genes. 2021 Oct;57(5):459-463. doi: 10.1007/s11262-021-01858-5. Epub 2021 Jun 29.

Abstract

Baculovirus infection modulates the chromatin states and gene expression of host insect cells. Here we performed chromatin immunoprecipitation followed by deep sequencing (ChIP-seq) of H3 trimethylated at Lys4 (H3K4me3) histone modification in Bombyx mori nucleopolyhedrovirus-infected Bombyx mori cells. The ChIP-seq data revealed the changes of the genome-wide distribution and accumulation of euchromatic histone marks in host insect cells during the progression of baculovirus infection.

Keywords: Baculovirus; BmNPV; ChIP-seq; H3K4me3; RNA-seq.

MeSH terms

  • Animals
  • Baculoviridae / genetics
  • Baculoviridae / pathogenicity
  • Bombyx / genetics*
  • Bombyx / virology
  • Chromatin / genetics*
  • Chromatin / virology
  • Gene Expression Regulation / genetics
  • High-Throughput Nucleotide Sequencing
  • Histone Code / genetics
  • Histones / genetics*
  • Nucleopolyhedroviruses / genetics*
  • Nucleopolyhedroviruses / pathogenicity
  • Protein Processing, Post-Translational / genetics

Substances

  • Chromatin
  • Histones
  • histone H3 trimethyl Lys4

Supplementary concepts

  • Bombyx mori nucleopolyhedrovirus