Oxidative stress induced by nanoplastics in the liver of juvenile large yellow croaker Larimichthys crocea

Li'ang Li; Huaxin Gu; Xueqing Chang; Wei Huang; Inna M Sokolova; Shuaishuai Wei; Li Sun; Shanglu Li; Xinghuo Wang; Menghong Hu; Jiangning Zeng; Youji Wang

doi:10.1016/j.marpolbul.2021.112661

Oxidative stress induced by nanoplastics in the liver of juvenile large yellow croaker Larimichthys crocea

Mar Pollut Bull. 2021 Sep:170:112661. doi: 10.1016/j.marpolbul.2021.112661. Epub 2021 Jun 25.

Authors

Li'ang Li¹, Huaxin Gu², Xueqing Chang¹, Wei Huang³, Inna M Sokolova⁴, Shuaishuai Wei¹, Li Sun⁵, Shanglu Li⁶, Xinghuo Wang¹, Menghong Hu¹, Jiangning Zeng⁷, Youji Wang⁸

Affiliations

¹ International Research Center for Marine Biosciences at Shanghai Ocean University, Ministry of Science and Technology, Shanghai Ocean University, Shanghai 201306, China; Key Laboratory of Exploration and Utilization of Aquatic Genetic Resources, Ministry of Education, Shanghai Collaborative Innovation for Aquatic Animal Genetics and Breeding, Shanghai Ocean University, China.
² International Research Center for Marine Biosciences at Shanghai Ocean University, Ministry of Science and Technology, Shanghai Ocean University, Shanghai 201306, China; Key Laboratory of Marine Ecosystem Dynamics, Second Institute of Oceanography, Ministry of Natural Resources, Hangzhou 310012, China; State Key Laboratory of Satellite Ocean Environment Dynamics, Second Institute of Oceanography, Ministry of Natural Resources, Hangzhou 310012, China; Key Laboratory of Exploration and Utilization of Aquatic Genetic Resources, Ministry of Education, Shanghai Collaborative Innovation for Aquatic Animal Genetics and Breeding, Shanghai Ocean University, China.
³ Key Laboratory of Marine Ecosystem Dynamics, Second Institute of Oceanography, Ministry of Natural Resources, Hangzhou 310012, China; State Key Laboratory of Satellite Ocean Environment Dynamics, Second Institute of Oceanography, Ministry of Natural Resources, Hangzhou 310012, China. Electronic address: willhuang@sio.org.cn.
⁴ Department of Marine Biology, Institute for Biological Sciences, University of Rostock, Rostock, Germany; Department of Maritime Systems, Interdisciplinary Faculty, University of Rostock, Rostock, Germany.
⁵ State Research Center of Island Exploitation and Management, Second Institute of Oceanography, Ministry of Natural Resources, Hangzhou 310012, China.
⁶ Zhejiang Ocean Monitoring and Forecasting Center, Hangzhou 310007, China.
⁷ Key Laboratory of Marine Ecosystem Dynamics, Second Institute of Oceanography, Ministry of Natural Resources, Hangzhou 310012, China; State Key Laboratory of Satellite Ocean Environment Dynamics, Second Institute of Oceanography, Ministry of Natural Resources, Hangzhou 310012, China.
⁸ International Research Center for Marine Biosciences at Shanghai Ocean University, Ministry of Science and Technology, Shanghai Ocean University, Shanghai 201306, China; Key Laboratory of Exploration and Utilization of Aquatic Genetic Resources, Ministry of Education, Shanghai Collaborative Innovation for Aquatic Animal Genetics and Breeding, Shanghai Ocean University, China. Electronic address: youjiwang2@gmail.com.

PMID: 34182302
DOI: 10.1016/j.marpolbul.2021.112661

Abstract

There are many toxicological studies on microplastics, but little is known about the effect of nanoplastics (NPs). Here, we evaluated the oxidative stress responses induced by NPs (10, 10⁴ and 10⁶ particles/l) in juvenile Larimichthys crocea during 14-d NPs exposure followed by a 7-d recovery. After exposure, the activities of antioxidant enzymes (SOD, CAT, GPx) and MDA levels increased in the liver of fish at the highest NPs concentration. SOD and CAT activities remained elevated above the baseline after recovery under high-concentration NPs but returned to the baseline in two other NP treatments. Although lipid peroxidation in liver was reversible, juvenile fish in NPs treatments exhibited a lower survival rate than the control during both exposure and recovery. Furthermore, IBR value and PCA analysis showed the potential adverse effects of NPs. Considering that NPs can reduce the survival of fish juveniles, impacts of NPs on fishery productivity should be considered.

Keywords: Juvenile fish; Larimichthys crocea; Nanoplastics; Oxidative stress; Survival.

MeSH terms

Animals
Fish Proteins / metabolism
Liver / metabolism
Microplastics*
Oxidative Stress
Perciformes* / metabolism
Plastics / metabolism

Substances

Fish Proteins
Microplastics
Plastics