Reusable Manganese Catalyst for Site-Selective Pyridine C-H Arylations and Alkylations

Abstract

Herein, we disclose a recyclable, hybrid manganese catalyst for site-selective azine C-H activation by weak amide assistance. The novel, reusable catalyst enabled C3-H arylation and C3-H alkylation with ample scope, and was characterized by detailed transmission electron microscopy analysis.

Keywords: C−H alkylation; C−H arylation; hybrid catalysis; manganese catalysis; site-selectivity.