Expected Versus Experienced Health-Related Quality of Life Among Patients Recovering From Cancer Surgery: A Prospective Cohort Study

Nikhil Panda; Ian Solsky; Brandon J Neal; Becky Hawrusik; Stuart Lipsitz; Carrie C Lubitz; Chris Gibbons; Mary Brindle; Robert D Sinyard; Jukka-Pekka Onnela; Christy E Cauley; Alex B Haynes

doi:10.1097/AS9.0000000000000060

Expected Versus Experienced Health-Related Quality of Life Among Patients Recovering From Cancer Surgery: A Prospective Cohort Study

Ann Surg Open. 2021 Apr 8;2(2):e060. doi: 10.1097/AS9.0000000000000060. eCollection 2021 Jun.

Authors

Nikhil Panda^{1

2}, Ian Solsky^{1

3}, Brandon J Neal¹, Becky Hawrusik¹, Stuart Lipsitz¹, Carrie C Lubitz^{1

2

4}, Chris Gibbons⁵, Mary Brindle^{1

2}, Robert D Sinyard^{1

2}, Jukka-Pekka Onnela^{1

5}, Christy E Cauley^{1

2}, Alex B Haynes^{1

6}

Affiliations

¹ Ariadne Labs, Brigham and Women's Hospital, Harvard. T.H. School of Public Health, Boston, MA.
² Department of Surgery, Massachusetts General Hospital, Boston, MA.
³ Department of Surgery, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, NY.
⁴ Institute for Technology Assessment, Massachusetts General Hospital, Boston MA.
⁵ Department of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, MA.
⁶ Department of Surgery and Perioperative Care, Dell Medical School, The University of Texas at Austin, Austin, TX.

Abstract

Patient expectations of the impact of surgery on postoperative health-related quality of life (HRQL) may reflect the effectiveness of patient-provider communication. We sought to compare expected versus experienced HRQL among patients undergoing cancer surgery.

Methods: Adults undergoing cancer surgery were eligible for inclusion (2017-2019). Preoperatively, patients completed a smartphone-based survey assessing expectations for HRQL 1 week and 1, 3, and 6 months postoperatively based on the 8 short-form 36 (SF36) domains (physical functioning, physical role limitations, pain, general health, vitality, social functioning, emotional role limitations, and mental health). Experienced HRQL was then assessed through smartphone-based SF36 surveys 1, 3, and 6 months postoperatively. Correlations between 1- and 6-month trends in expected versus experienced HRQL were determined.

Results: Among 101 consenting patients, 74 completed preoperative expectations and SF36 surveys (73%). The mean age was 54 years (SD 14), 49 (66%) were female, and the most common operations were for breast (34%) and abdominal (31%) tumors. Patients expected HRQL to worsen 1 week after surgery and improve toward minimal disability over 6 months. There was poor correlation (≤±0.4) between 1- and 6-month trends in expected versus experienced HRQL in all SF36 domains except for moderate correlation in physical functioning (0.50, 95% confidence interval [0.22-0.78], P < 0.001) and physical role limitations (0.41, 95% confidence interval [0.05-0.77], P = 0.024). Patients expected better HRQL than they experienced.

Conclusions: Preoperative expectations of postoperative HRQL correlated poorly with lived experiences except in physical health domains. Surgeons should evaluate factors which inform expectations around physical and psychosocial health and use these data to enhance shared decision-making.

Keywords: cancer surgery; expectations; health-related quality of life; patient-reported outcome measures.

Abstract

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