Although subacute sclerosing panencephalitis is almost exclusively a childhood disease, it can occur in adults as well. We present an atypical case of adult-onset subacute sclerosing panencephalitis. The disease was characterized by prolonged insidious course followed by accelerated and aggressive phase, atypical EEG findings, and absence of myoclonic jerks. The diagnostic and treatment-related pitfalls are discussed.
Keywords: Adult onset; MRZ (measles, rubella, varicella-zoster) reaction; Multiple sclerosis; Subacute sclerosing panencephalitis.