IgA Vasculitis in an Oldest-old Patient Successfully Treated with Glucocorticoid

Intern Med. 2022 Jan 15;61(2):213-216. doi: 10.2169/internalmedicine.7576-21. Epub 2021 Jun 26.

Abstract

A 94-year-old man was diagnosed with immunoglobulin A vasculitis (IgAV), and losartan was initiated. His renal function rapidly deteriorated over a month; therefore, methylprednisolone was administered intravenously for three days followed by oral prednisolone. Renal function improvement and both proteinuria and hematuria remission were observed within six months. Prednisolone tapering was completed at eight months. In this case, we monitored the patient carefully and started glucocorticoids as soon as the patient's renal function deteriorated. We were thus able to treat the patient with a relatively small dose of glucocorticoids in a short treatment period without any adverse events due to glucocorticoids.

Keywords: IgA vasculitis; glucocorticoid; oldest-old.

Publication types

  • Case Reports

MeSH terms

  • Aged, 80 and over
  • Glucocorticoids*
  • Hematuria
  • Humans
  • IgA Vasculitis*
  • Immunoglobulin A
  • Male
  • Methylprednisolone / therapeutic use
  • Proteinuria

Substances

  • Glucocorticoids
  • Immunoglobulin A
  • Methylprednisolone