A comprehensive review on chemotherapeutic potential of galangin

Biomed Pharmacother. 2021 Sep:141:111808. doi: 10.1016/j.biopha.2021.111808. Epub 2021 Jun 24.

Abstract

Galangin, a non-toxic phytochemical is known to possess several therapeutic applications. Mounting evidences have demonstrated that galangin a naturally available flavonoid exerts anticancer effects via several mechanisms. The phytocompound induces apoptosis and renders antiangiogenic property. Additionally, galangin has demonstrated significate results in combating various cancer types when administered in combination with other phytocompounds or with gold nanoparticles (GNPs). The present article is a critical review of galangin for its treatment on different types of cancer and its usability as an alternative cancer therapeutics.

Keywords: Anticancer phytochemical; Cancer; Flavonoid; Flavonol; Galangin.

Publication types

  • Review

MeSH terms

  • Angiogenesis Inhibitors / pharmacology
  • Angiogenesis Inhibitors / therapeutic use
  • Animals
  • Antineoplastic Agents, Phytogenic / pharmacology
  • Antineoplastic Agents, Phytogenic / therapeutic use*
  • Apoptosis / drug effects
  • Flavonoids / therapeutic use*
  • Gold
  • Humans
  • Metal Nanoparticles
  • Neoplasms / drug therapy*
  • Phytotherapy

Substances

  • Angiogenesis Inhibitors
  • Antineoplastic Agents, Phytogenic
  • Flavonoids
  • galangin
  • Gold