Blalock-Taussig Shunt versus Ductal Stent in the Palliation of Duct Dependent Pulmonary Circulation; A Systematic Review and Metanalysis

Curr Probl Cardiol. 2022 Sep;47(9):100885. doi: 10.1016/j.cpcardiol.2021.100885. Epub 2021 May 8.

Abstract

In infants with ductal dependent pulmonary blood flow, Blalock-Taussig (BT) shunt and Patent Ductus Arteriosus (PDA) stent, are two palliative procedures aimed to restore circulation. A systematic review and metanalysis was performed on studies comparing PDA stents and BT shunts, in accordance with PRISMA guidelines. Meta-analysis revealed the following; (1) a reduced risk of mortality [RR = 0.585 [0.399-0.859], (P = 0.006)], (2) a reduced risk of complications [RR = 0.523 [0.318-0.860], (P = 0.011), and (3) a reduced risk of ECMO use [R = 0.267 [0.101-0.706] (P = 0.008)], all in the stent group. Additionally, stent group showed higher post procedure oxygen saturation [SMD = 1.307 [95% CI 1.065-1.550], (P < 0.001)], and Nakata index [SMD = 0.679 95% CI [0.513 to 0.845], (P < 0.001)]. PDA stenting presents a viable alternative to BT shunt procedure with better post procedure stability.

Publication types

  • Meta-Analysis
  • Review
  • Systematic Review

MeSH terms

  • Blalock-Taussig Procedure* / adverse effects
  • Cardiac Catheterization
  • Ductus Arteriosus, Patent* / surgery
  • Humans
  • Pulmonary Artery / surgery
  • Pulmonary Circulation
  • Stents
  • Treatment Outcome