Leiomyosarcoma of the male breast: Case report

Ann Med Surg (Lond). 2021 Jun 9:67:102495. doi: 10.1016/j.amsu.2021.102495. eCollection 2021 Jul.

Abstract

Introduction: Primary sarcoma in man is very rare and knowledge about this tumor is limited with very few cases published in the literature.

Case report: A 65-year-old man operated on 20 years ago for a left breast tumor with a skin graft at the tumor site (no documentation or pathology report). He consulted for a mass in the left breast, bleeding on contact, associated with nodules in the right breast that looked suspicious. On breast ultrasound, a tissue formation in the lower medial quadrant of the left breast with irregular contours, measuring 42 × 53mm with the presence of several suspicious tissue formations in the right breast, the largest measuring 2 × 2cm.Surgical removal of the left mass with a right mastectomy with pathology report of breast leiomyosarcoma with healthy surgical borders followed by radiotherapy for local control.

Discussion: Leiomyosarcoma is an extremely rare tumor in the breast and usually originates from the blood vessels, myoepithelium, or nipple musculature, as in our case. Breast sarcomas represent less than 1% of all malignant neoplasms of the breast. Their incidence in women is much higher than in men.

Conclusion: Primary breast sarcomas are rare tumors that originate from the mesenchymal tissue of the breast and represent less than 1% of all malignant neoplasms of the breast. Their diagnosis is confirmed by biopsy with immunohistochemical and only surgery can guarantee cure. Radiotherapy is recommended for local control after surgery.

Keywords: Breast; Case report; Leiomyosarcoma; Male; Radiotherapy.

Publication types

  • Case Reports