A detailed review of the outbreak of COVID-19

Front Biosci (Landmark Ed). 2021 May 30;26(6):149-170. doi: 10.52586/4931.

Abstract

The disease COVID-19 caused by SARS-CoV-2 is the third highly infectious human Coronavirus epidemic in the 21s⁢t century due to its high transmission rate and quick evolution of its pathogenicity. Genomic studies indicate that it is zoonotic from bats. The COVID-19 has led to significant loss of lives and a tremendous economic decline in the world. Generally, the population at risk of a fatal outcome are the elderly and those who are debilitated or are immune compromised. The fatality rate is high, but now is reduced after the development of preventive vaccine although an effective treatment by drug against the virus is yet to be developed. The treatment is narrowed to the use of several anti-viral drugs, or other re-purposed drugs. Social distancing, therefore, has emerged as a putative method to decrease the rate of infection. In this review, we summarize the aspects of the disease that is so far have come to light and review the impact of the infection on our society, healthcare, economy, education, and environment.

Keywords: COVID-19; Phronetic needs for COVID-19; SARS-CoV-2; Socio-economic impacts; Therapeutics; Vaccine development.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Antiviral Agents / therapeutic use*
  • COVID-19 / epidemiology
  • COVID-19 / virology
  • COVID-19 Drug Treatment*
  • COVID-19 Vaccines / administration & dosage*
  • COVID-19 Vaccines / immunology
  • Communicable Disease Control / methods*
  • Disease Outbreaks / prevention & control
  • Hand Disinfection / methods
  • Humans
  • Physical Distancing
  • Public Health / economics
  • Public Health / methods
  • SARS-CoV-2 / drug effects*
  • SARS-CoV-2 / immunology
  • SARS-CoV-2 / physiology

Substances

  • Antiviral Agents
  • COVID-19 Vaccines